Posts Tagged ‘Levaquin Antibiotic’

Permanent Side Effect Linked to Levaquin

Thursday, December 11th, 2008


An antibiotic used to treat an array of bacterial infections among adults was approved recently by the Food and Drug Administration (FDA) for children.

Levaquin levofloxacin is part of the fluoroquinolone group of oral medications prescribed to treat acute bacterial sinusitis, acute bacterial exacerbation of chronic bronchitis, noscocomial pneumonia, community-acquired pneumonia, complicated skin and skin structure infections, mild to moderate uncomplicated skin and skin structure infections, chronic bacterial prostates, urinary tract infections and acute pyelonephritis caused by Escherichia coli, also known as E. coli, which is an infection affecting the lower intestines of humans and highly associated with food poisonings in the United States. The drugLevaquin, which is manufactured by from pharmaceutical firm Ortho-McNeil, was approved in 1996, but the oral solution was introduced in 2004 and this was followed by a 750-milligrams (mg) five-day oral treatment becoming widely available in 2005, although the Levaquin is also available intravenously as well.

While Levaquin is prescribed for an array of bacterial infections, it has also been approved to treat the effects of airborne anthrax. It was also recently approved for the use by in treating children as an anti-bacterial component and as a treatment of anthrax contamination among children as well. The drug is absorbed quickly, particularly after oral consumption and is usually allotted in 500 mg to 750 mg doses.

According to manufacturers, individuals who have kidney disease, diabetes, spinal or brain cord conditions are highly recommended to avoid the drug as it could cause serious side eaffects including:

* slow absorption of in kidney disease patients

* blood level spikes and irregularities of in diabetes patients

* uncontrollable seizures among spinal and brain injury patients

Levaquin Side Effects

According to manufacturers, the most common adverse drug reactions Levaquin side effects that occurred in U.S. clinical trials of Levaquin included headache, nausea and diarrhea, constipation, dizziness and insomnia. Additionally, the list of side effects continues to grow and patients thatwith exude any of the following symptoms should stop taking the medication and seek medical assistance immediately:

* abdominal tenderness, cramping or severe pain

* confusion, hallucinations or psychosis

* diarrhea (which may be bloody)

* fever

* blisters, redness and swelling of the skin

* sensation of burning skin

* trembling or seizures

* vomiting

* easy bruising or bleeding

* jaundice

* numbness in limbs, tingling in fingers

* swelling, pain in legs/muscles

Recent studies have also suggested that individuals with preexisting conditions (previously mentioned) as well as individuals taking specific types of medicine may increase their risk of these Levaquin side effects causing severe medical trauma.

Complications may occur when use of Levaquin is combined with:

* blood thinners (warfarin/coumadin)

* cyclosporine

* insulin

* theophylline

* aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs)

* heart rhythm medications (Cordarone, Pacerone, etc.)

* antacids (Tums, Rolaids)

* ulcer medication (Carafate)

* didanosine (Videx)

* vitamins or supplements containing iron or zinc

Levaquin Tendon Rupture Risks

The most serious Levaquin side effect is the risk of Achilles tendonitis among current and former patients of Levaquin levofloxacin. Several studies published in accredited medical journals including the Journal of Antimicrobial Chemotherapy, The Journal of the American Board of Family Medicine, The Annals of Pharmacotherapy and Tthe Journal of Orthopaedics and Traumatology have all cited case studies in which individuals who have taken Levaquin have been adversely affected by levofloxacin-induced tendonopathy and tendon rupture.

According to the report from The Journal of American Board of Family Medicine, the onset of tendon ruptures among patients characteristically is abrupt in onset causing extreme sharp pains and swelling of legs when walking. The study also reports that while most of the tendonitis among Leva

quin patients occurs within the first two weeks of taking the drug., Hhowever, it can occur in patients long after the drug’s cycle has been completed.

In some patients, the Levaquin tendon ruptures occurred longer than six months after treatment administration of the drug. The study noted that the U.S. Food and Drug Administration (FDA ) first cited the link of tendon rupture to drugs in the quinolone drug class was in 1991.

Although it wasn’t until 1996 when the FDA issued its first “Report of adverse Events” on the fluoroquinolones. However, since then, it has been recorded that at least 200 reports of tendon rupture induced through the class of drugs has been reported within a 10-year period and no recall or major investigation has occurred to increase warning labelings on the drugs, especially Levaquin. Additionally, a report from the United Kingdom found that levofloxacin-induced tendonitis potentially affects approximately 3.2 out of approximatly every 1,000 Levaquin patients who have taken the drug at some point.

Victims of Levaquin Risks

Individuals who have previously been exposed totaken Levaquin, whether through intravenous or oral methods, should speak with their physician to asses any potential risk. Additionally, patients may which to consult with an experienced Levaquin lawyer a pharmaceutical lawyer especially if any of the previous symptoms have occurred. Additionally, because of the severity of tendonitis and potential long-term damage done, it is important for an individual to consider seeking out compensation in the form of a Levaquin Lawsuit that may provide monetary relief from the extensive surgical and medical procedures likely associated with solving or easing the pain of tendonitis caused through a prescription of Levaquinby having taken Levaquin.

Levaquin side effects-tendons

Tuesday, February 12th, 2008


I’m 53 years old and active. 11 weeks ago I took Levaquin for 14 days. I had slight tendon side effects during treatment. After treatment, effects got worse – pain countenance within the load bearing ligaments and the achilles heels. The pain was crippling. In this account, I’ll refer to time in weeks since stopping Levaquin.
After 1 week, I started reading forums, physicians’ accounts, and all These will scare the hell out of you – ruptured tendons, recovery periods lasting years, and so on and so fourth The following were the most useful: 1) One physician’s report states that he had 4 patients with ligament side effects. Of the 4, 1 recovered in 3 weeks and all recovered within 3 months. 2) A physical therapist provides a brilliant case history.(Google “Dr Greene physical therapy levaquin tendons”.) In this, the patient sees his first therapist for 4 weeks with poor results. He begins with Dr. Greene. For 7 weeks the goal is, protect the heels. Over the next 4 weeks they begin “loading” his tendons and he improves greatly. At 5? months, he’s fully recovered. 3) each and every persons’ recovery period is unique. Some recover in days, others weeks, months or years. But, all seem to recover. 4) Recovery is not linear. You experience improvement one day only to have it reversed the next. you can most defiantly plateau for weeks with no progress.(Items 3 and 4, are very frustrating causing fantastic anxiety.) 5) A small tip: before injury, I owned quality hiking sandals with spongy soles and adjustable straps. During my recovery, these have been lifesavers since I wear the sandals with the back straps loose applying no pressure on the excellent heels. 6) Everybody will offer advice, but they have no idea what you’re going through or how to cure you. There is no magic pill. Time is the unsurpassed medicine. FYI: I take: Aleve, collagen, magnesium, calcium, chondroitin and a multivitamin.
My case report:
Weeks 1 and 2 - I was flat on my back always uncomfortable or in pain. If I owned crutches, I could’ve new them.
Weeks 3 to 4 - I would move around the house with sore leg tendons and stiff painful heels. Most nights I had gone to bed in pain, waking up feeling stiff and sore but better. Soon feeling worse. Not being able to leave the house even to go to the mail box without raising pain and feeling tired. Anxiety setting in.
Weeks 4 to 6 – Some improvement, now moving around the house with only stiffness and soreness. had gone to supermarket but had to set down at register and for several days had pain increased. Frustrated and worried to tears.
Weeks 7 and 8 – No change. Recovery clearly going to take three or more months. I filed an FDA Med Watch Report.
Weeks 9 and 10 – A little progress, stretching both leg and heel tendons but they remain tight. Tire easily. Despair is setting in. Considering life as a cripple.
Week 11 – Out of nowhere, burst of improvement. first day of the week, Sunday, started out classically. Later felt better and rode bike a short distance (easy on the magnificent heels). When I returned, my legs were tired but a couple hours later felt better. So, I took my son to the tennis court and hit balls to him. The legs got tight and achy, but no carryover pain to next day. Monday, rode the bike a little further. Later, had gone to tennis courts to hit a few balls with friends. Couldn’t cover a vast number of ground and after 15 minutes was done. But again, no carryover pain. Tuesday, rode bike again going further. Later, played doubles (standing in one place) with boys resting on the high-school team. Managed to play an hour still stiff and sore the whole time. On Wednesday, had gone shopping to several stores. Still sore and tight, but recovered in an hour. Later, hit balls for a couple of hours with restricted movement but for the first ? hour, little soreness or pain. Later, the heels tight. But, after sitting down 15 minutes, continued for another hour with soreness. Again, no carryover pain to today.
I’m now hoping for full recovery between 3 and 5 month period noted in 1 and 2 above.
Hope this is handy.